Endocrine Abstracts

Background: Immune related adverse events (iRAEs) of the endocrine system are commonly recognised in Checkpoint Inhibitor (CTLA-4 and PD-1 inhibitors) Therapy. Clinically, endocrinopathies can present with symptoms of hormone deficiency, hormone excess or both (in the same or different glands).Aim: Audit of Incidence and Management (detection, investigation, referral and management) practices of Endocrinopathies due to Immunotherapy in Oncology departmen...

Background and Aim: RAIT is successful in achieving cure of thyrotoxicosis. However, 10-15% patients require further doses, usually administered at 4-6 months after the initial dose. We assessed the role of TRAB values in predicting the need for redosing, which could have useful implications.Patients and Methods: We measured TRAB at diagnosis and at the time of 550MBq RAIT in 54 patients with Graves’ disease. We rec...